| 1 | Mon Nov 3 | at Bowling Green | L48-83 | 0-1 | .000 | - | ESPN+ | Stroh Center · Bowling Green, OH |
| 2 | Wed Nov 5 | vs TBD | W114-55 | 1-1 | .500 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 3 | Sat Nov 8 | at Tulane | L71-79 | 1-2 | .333 | - | ESPN+ | Devlin Fieldhouse · New Orleans, LA |
| 4 | Wed Nov 12 | vs UTSA | W80-69 | 2-2 | .500 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 5 | Sat Nov 15 | vs Texas So | W77-67 | 3-2 | .600 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 6 | Tue Nov 18 | vs Abilene Chrstn | W63-49 | 4-2 | .667 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 7 | Fri Nov 21 | vs Little Rock | W65-56 | 5-2 | .714 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 8 | Mon Nov 24 | vsTBD | W93-41 | 6-2 | .750 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 9 | Fri Nov 28 | at Seattle U | L52-66 | 6-3 | .667 | - | | Redhawk Center · Seattle, WA |
| 10 | Sat Nov 29 | vs Lehigh | L74-78 (OT) | 6-4 | .600 | - | | Strahan Arena · San Marcos, TX |
| 11 | Wed Dec 3 | at Rice | L72-77 | 6-5 | .545 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 12 | Wed Dec 10 | vs Southern | W86-83 | 7-5 | .583 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 13 | Wed Dec 17 | vs Arkansas St | L70-89 | 7-6 | .538 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 14 | Sat Dec 20 | vs South Alabama | W67-65 | 8-6 | .571 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 15 | Wed Dec 31 | at Troy | L80-100 | 8-7 | .533 | - | ESPN+ | Trojan Arena · Troy, AL |
| 16 | Sat Jan 3 | at UL Monroe | W84-79 | 9-7 | .563 | - | ESPN+ | Fant-Ewing Coliseum · Monroe, LA |
| 17 | Thu Jan 8 | at Southern Miss | L70-80 (OT) | 9-8 | .529 | - | ESPN+ | Reed Green Coliseum · Hattiesburg, MS |
| 18 | Sat Jan 10 | atArkansas St | L82-83 | 9-9 | .500 | - | ESPN+ | First National Bank Arena · Jonesboro, AR |
| 19 | Wed Jan 14 | vs Louisiana | W59-54 | 10-9 | .526 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 20 | Sat Jan 17 | vsSouthern Miss | W74-67 | 11-9 | .550 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 21 | Thu Jan 22 | at Coast Car | L70-72 | 11-10 | .524 | - | ESPN+ | The HTC Center · Conway, SC |
| 22 | Sat Jan 24 | at JMU | L57-82 | 11-11 | .500 | - | ESPN+ | Atlantic Union Bank Center · Harrisonburg, VA |
| 23 | Wed Jan 28 | vs Marshall | W72-68 | 12-11 | .522 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 24 | Sat Jan 31 | vs Old Dominion | W81-64 | 13-11 | .542 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 25 | Wed Feb 4 | at Georgia So | W77-71 | 14-11 | .560 | - | ESPN+ | W.S. Hanner Fieldhouse · Statesboro, GA |
| 26 | Sat Feb 7 | vs W Michigan | W77-61 | 15-11 | .577 | - | ESPN+ | Strahan Arena · San Marcos, TX |
Appalachian St