| 1 | Sat Nov 8 | vs San Francisco | W76-70 | 1-0 | 1.000 | - | ESPN+ | FedExForum · Memphis, TN |
| 2 | Tue Nov 11 | at Ole Miss | L77-83 | 1-1 | .500 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 3 | Sun Nov 16 | vs UNLV | L78-92 | 1-2 | .333 | - | ESPN | FedExForum · Memphis, TN |
| 4 | Thu Nov 20 | at #1Purdue | L71-80 | 1-3 | .250 | - | CBSSN | Mackey Arena · West Lafayette, IN |
| 5 | Fri Nov 21 | vs Wake Forest | L68-69 | 1-4 | .200 | - | CBSSN | FedExForum · Memphis, TN |
| 6 | Wed Nov 26 | vs S Illinois | W74-58 | 2-4 | .333 | - | ESPN+ | FedExForum · Memphis, TN |
| 7 | Wed Dec 3 | vs New Orleans | W86-70 | 3-4 | .429 | - | ESPN+ | FedExForum · Memphis, TN |
| 8 | Sat Dec 6 | vs Baylor | W78-71 | 4-4 | .500 | - | CBS | FedExForum · Memphis, TN |
| 9 | Sat Dec 13 | at #11Louisville | L73-99 | 4-5 | .444 | - | ESPN | KFC Yum! Center · Louisville, KY |
| 10 | Wed Dec 17 | vs #13Vanderbilt | L70-77 (OT) | 4-6 | .400 | - | ESPN2 | FedExForum · Memphis, TN |
| 11 | Sat Dec 20 | at Mississippi St | L66-71 | 4-7 | .364 | - | ESPN | Humphrey Coliseum · Starkville, MS |
| 12 | Mon Dec 22 | vs Alabama St | W88-67 | 5-7 | .417 | - | | FedExForum · Memphis, TN |
| 13 | Wed Dec 31 | vs North Texas | W57-48 | 6-7 | .462 | - | ESPN2 | FedExForum · Memphis, TN |
| 14 | Sat Jan 3 | at Rice | W76-70 | 7-7 | .500 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 15 | Sun Jan 11 | at FAU | L78-89 | 7-8 | .467 | - | ESPN2 | FAU Arena · Boca Raton, FL |
| 16 | Wed Jan 14 | vs Temple | W55-53 | 8-8 | .500 | - | ESPN+ | FedExForum · Memphis, TN |
| 17 | Sun Jan 18 | vs UTSA | W95-69 | 9-8 | .529 | - | ESPNU | FedExForum · Memphis, TN |
| 18 | Wed Jan 21 | at Tulsa | L66-83 | 9-9 | .500 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 19 | Sat Jan 24 | at Wichita St | L59-74 | 9-10 | .474 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 20 | Thu Jan 29 | vsFAU | W92-65 | 10-10 | .500 | - | ESPN2 | FedExForum · Memphis, TN |
| 21 | Sun Feb 1 | vs Tulane | L76-78 | 10-11 | .476 | - | ESPN2 | FedExForum · Memphis, TN |
| 22 | Thu Feb 5 | at UAB | W90-80 | 11-11 | .500 | - | ESPN2 | Bartow Arena · Birmingham, AL |
| 23 | Sun Feb 8 | vs Charlotte | W77-54 | 12-11 | .522 | - | ESPN+ | FedExForum · Memphis, TN |
Utah State
South Florida
E Carolina