| 1 | Mon Nov 3 | vs UT Rio Grande | W96-81 | 1-0 | 1.000 | - | ESPN+ | Ferrell Center · Waco, TX |
| 2 | Sun Nov 9 | vs Washington | W78-69 | 2-0 | 1.000 | - | ESPN | Ferrell Center · Waco, TX |
| 3 | Fri Nov 14 | vs Tarleton | W94-81 | 3-0 | 1.000 | - | ESPN+ | Ferrell Center · Waco, TX |
| 4 | Mon Nov 24 | vs Creighton | W81-74 | 4-0 | 1.000 | - | truTV | Ferrell Center · Waco, TX |
| 5 | Tue Nov 25 | vs #14St John's | L81-96 | 4-1 | .800 | - | truTV | Ferrell Center · Waco, TX |
| 6 | Wed Nov 26 | at SDSU | W91-81 | 5-1 | .833 | - | truTV | Viejas Arena · San Diego, CA |
| 7 | Tue Dec 2 | vs Sacramento St | W110-88 | 6-1 | .857 | - | ESPN+ | Ferrell Center · Waco, TX |
| 8 | Sat Dec 6 | at Memphis | L71-78 | 6-2 | .750 | - | CBS | FedExForum · Memphis, TN |
| 9 | Wed Dec 10 | vs Norfolk St | W97-67 | 7-2 | .778 | - | ESPN+ | Ferrell Center · Waco, TX |
| 10 | Fri Dec 19 | vs Alcorn St | W113-56 | 8-2 | .800 | - | ESPN+ | Ferrell Center · Waco, TX |
| 11 | Sun Dec 21 | vs Southern | W111-67 | 9-2 | .818 | - | TNT | Ferrell Center · Waco, TX |
| 12 | Mon Dec 29 | vs TBD | W124-61 | 10-2 | .833 | - | ESPN+ | Ferrell Center · Waco, TX |
| 13 | Sat Jan 3 | at TCU | L63-69 | 10-3 | .769 | - | TNT | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 14 | Wed Jan 7 | vs #3Iowa State | L60-70 | 10-4 | .714 | - | Peacock | Ferrell Center · Waco, TX |
| 15 | Sat Jan 10 | vs #7Houston | L55-77 | 10-5 | .667 | - | Peacock | Ferrell Center · Waco, TX |
| 16 | Tue Jan 13 | at Oklahoma St | W94-79 | 11-5 | .688 | - | CBSSN | Gallagher-Iba Arena · Stillwater, OK |
| 17 | Fri Jan 16 | at Kansas | L62-80 | 11-6 | .647 | - | FOX | Allen Fieldhouse · Lawrence, KS |
| 18 | Tue Jan 20 | vs #12Texas Tech | L73-92 | 11-7 | .611 | - | Peacock | Ferrell Center · Waco, TX |
| 19 | Sat Jan 24 | vsTCU | L90-97 | 11-8 | .579 | - | ESPN | Ferrell Center · Waco, TX |
| 20 | Wed Jan 28 | at Cincinnati | L57-67 | 11-9 | .550 | - | FS1 | Fifth Third Arena · Cincinnati, OH |
| 21 | Sat Jan 31 | at West Virginia | W63-53 | 12-9 | .571 | - | ESPN2 | WVU Coliseum · Morgantown, WV |
| 22 | Wed Feb 4 | vs Colorado | W86-67 | 13-9 | .591 | - | Peacock | Ferrell Center · Waco, TX |
| 23 | Sat Feb 7 | at#7Iowa State | L69-72 | 13-10 | .565 | - | ESPN | James H. Hilton Coliseum · Ames, IA |
#22BYU
#24Louisville
Kansas St
Arizona St
#1Arizona
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