| 1 | Mon Nov 3 | vs Towson | L56-67 | 0-1 | .000 | - | | Reitz Arena · Baltimore, MD |
| 2 | Thu Nov 6 | vs TBD | W96-60 | 1-1 | .500 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 3 | Tue Nov 11 | vs NJIT | L64-66 | 1-2 | .333 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 4 | Sat Nov 15 | at Stonehill | W74-63 | 2-2 | .500 | - | ESPN+ | Leo D. Mahoney Arena · Fairfield, CT |
| 5 | Sun Nov 16 | at Fairfield | L82-85 | 2-3 | .400 | - | ESPN+ | Leo D. Mahoney Arena · Fairfield, CT |
| 6 | Wed Nov 19 | at Duquesne | L78-92 | 2-4 | .333 | - | ESPN+ | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 7 | Fri Nov 21 | at #12Kentucky | L46-88 | 2-5 | .286 | - | SECN+ | Rupp Arena · Lexington, KY |
| 8 | Tue Nov 25 | vsTBD | W101-51 | 3-5 | .375 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 9 | Sun Nov 30 | vs Coppin St | W95-84 | 4-5 | .444 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 10 | Wed Dec 3 | at Hampton | L71-93 | 4-6 | .400 | - | | Convocation Center (VA) · Hampton, VA |
| 11 | Tue Dec 9 | at VMI | L70-86 | 4-7 | .364 | - | ESPN+ | Cameron Hall · Lexington, VA |
| 12 | Sat Dec 13 | vs Mount St Mary | L73-81 | 4-8 | .333 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 13 | Sun Dec 21 | at George Mason | L79-86 | 4-9 | .308 | - | ESPN+ | EagleBank Arena · Fairfax, VA |
| 14 | Wed Dec 31 | at American | L69-84 | 4-10 | .286 | - | ESPN+ | Bender Arena · Washington, D.C. |
| 15 | Sat Jan 3 | vs Lafayette | L64-79 | 4-11 | .267 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 16 | Wed Jan 7 | at Army | W84-76 (OT) | 5-11 | .313 | - | ESPN+ | Christl Arena · West Point, NY |
| 17 | Sat Jan 10 | at Bucknell | L67-70 | 5-12 | .294 | - | ESPN+ | Sojka Pavilion · Lewisburg, PA |
| 18 | Wed Jan 14 | vs Colgate | L80-86 | 5-13 | .278 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 19 | Sat Jan 17 | vs Boston Univ | W74-57 | 6-13 | .316 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 20 | Mon Jan 19 | at Lehigh | L81-88 | 6-14 | .300 | - | CBSSN | Stabler Arena · Bethlehem, PA |
| 21 | Sat Jan 24 | vsBucknell | W67-62 | 7-14 | .333 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 22 | Wed Jan 28 | vsAmerican | W77-68 | 8-14 | .364 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 23 | Sat Jan 31 | at Navy | L71-87 | 8-15 | .348 | - | ESPN+ | Alumni Hall (Navy) · Annapolis, MD |
| 24 | Wed Feb 4 | vsLehigh | W89-84 (2OT) | 9-15 | .375 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 25 | Sat Feb 7 | atBoston Univ | L69-78 | 9-16 | .360 | - | ESPN+ | Case Gym · Boston, MA |
Holy Cross