| 1 | Wed Nov 5 | vs Coppin St | W87-59 | 1-0 | 1.000 | - | ESPN+ | Tom Gola Arena · Philadelphia, PA |
| 2 | Sat Nov 8 | vs Monmouth | W73-60 | 2-0 | 1.000 | - | ESPN+ | Tom Gola Arena · Philadelphia, PA |
| 3 | Tue Nov 11 | at Temple | L63-90 | 2-1 | .667 | - | ESPN+ | Liacouras Center · Philadelphia, PA |
| 4 | Sat Nov 15 | vs Penn State | L69-83 | 2-2 | .500 | - | Peacock | Tom Gola Arena · Philadelphia, PA |
| 5 | Wed Nov 19 | vs Villanova | L55-70 | 2-3 | .400 | - | CBSSN | Tom Gola Arena · Philadelphia, PA |
| 6 | Sat Nov 22 | vs TBD | W75-46 | 3-3 | .500 | - | ESPN+ | Tom Gola Arena · Philadelphia, PA |
| 7 | Fri Nov 28 | vs Hofstra | L58-63 | 3-4 | .429 | - | ESPN+ | The Palestra · Philadelphia, PA |
| 8 | Sat Nov 29 | at Penn | L71-73 | 3-5 | .375 | - | ESPN+ | The Palestra · Philadelphia, PA |
| 9 | Sun Nov 30 | vs Merrimack | L60-66 | 3-6 | .333 | - | ESPN+ | The Palestra · Philadelphia, PA |
| 10 | Sat Dec 6 | vs Drexel | W69-64 | 4-6 | .400 | - | | Tom Gola Arena · Philadelphia, PA |
| 11 | Sat Dec 13 | at Long Island | L60-70 | 4-7 | .364 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 12 | Fri Dec 19 | at High Point | L72-84 | 4-8 | .333 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 13 | Sun Dec 21 | at #2Michigan | L50-102 | 4-9 | .308 | - | Peacock | Crisler Center · Ann Arbor, MI |
| 14 | Wed Dec 31 | vs George Mason | L75-80 | 4-10 | .286 | - | ESPN+ | Tom Gola Arena · Philadelphia, PA |
| 15 | Sat Jan 3 | at G Washington | L55-77 | 4-11 | .267 | - | USA Net | Charles E. Smith Center · Washington, D.C. |
| 16 | Wed Jan 7 | at Rhode Island | W79-72 | 5-11 | .313 | - | ESPN+ | Ryan Center · Kingston, RI |
| 17 | Sat Jan 10 | vs Saint Louis | L72-84 | 5-12 | .294 | - | USA Net | Tom Gola Arena · Philadelphia, PA |
| 18 | Wed Jan 14 | at Richmond | L53-74 | 5-13 | .278 | - | ESPN+ | Robins Center · Richmond, VA |
| 19 | Sat Jan 17 | vs St Bonaventure | W78-74 | 6-13 | .316 | - | USA Net | Tom Gola Arena · Philadelphia, PA |
| 20 | Wed Jan 21 | vs Dayton | W67-64 | 7-13 | .350 | - | ESPN+ | Tom Gola Arena · Philadelphia, PA |
| 21 | Wed Jan 28 | at Fordham | L58-64 | 7-14 | .333 | - | ESPN+ | Rose Hill Gymnasium · Bronx, NY |
| 22 | Sat Jan 31 | vs Saint Joseph's | L58-67 | 7-15 | .318 | - | USA Net | Tom Gola Arena · Philadelphia, PA |
| 23 | Tue Feb 3 | at Loyola Chicago | L61-71 | 7-16 | .304 | - | ESPN+ | Joseph J. Gentile Arena · Chicago, IL |
| 24 | Sat Feb 7 | at#19Saint Louis | L58-82 | 7-17 | .292 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
VCU
Duquesne
Davidson