| 1 | Mon Nov 3 | vs Texas So | W98-43 | 1-0 | 1.000 | #21 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 2 | Sat Nov 8 | vs Oklahoma | W83-68 | 2-0 | 1.000 | #21 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 3 | Tue Nov 11 | vs #23Creighton | W90-63 | 3-0 | 1.000 | #19 | ESPN | McCarthey Athletic Center · Spokane, WA |
| 4 | Fri Nov 14 | at Arizona St | W77-65 | 4-0 | 1.000 | #19 | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 5 | Mon Nov 17 | vs Southern Utah | W122-50 | 5-0 | 1.000 | #13 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 6 | Mon Nov 24 | at #8Alabama | W95-85 | 6-0 | 1.000 | #12 | TNT | Coleman Coliseum · Tuscaloosa, AL |
| 7 | Tue Nov 25 | vs Maryland | W100-61 | 7-0 | 1.000 | #12 | truTV | McCarthey Athletic Center · Spokane, WA |
| 8 | Wed Nov 26 | at #7Michigan | L61-101 | 7-1 | .875 | #12 | TNT | Crisler Center · Ann Arbor, MI |
| 9 | Fri Dec 5 | at #18Kentucky | W94-59 | 8-1 | .889 | #11 | ESPN2 | Rupp Arena · Lexington, KY |
| 10 | Sun Dec 7 | vs North Florida | W109-58 | 9-1 | .900 | #11 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 11 | Sat Dec 13 | vs #25UCLA | W82-72 | 10-1 | .909 | #8 | ESPN | McCarthey Athletic Center · Spokane, WA |
| 12 | Wed Dec 17 | vs Campbell | W98-70 | 11-1 | .917 | #7 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 13 | Sun Dec 21 | at Oregon | W91-82 | 12-1 | .923 | #7 | Peacock | Matthew Knight Arena · Eugene, OR |
| 14 | Sun Dec 28 | at Pepperdine | W96-56 | 13-1 | .929 | #7 | ESPN+ | Firestone Fieldhouse · Malibu, CA |
| 15 | Tue Dec 30 | at San Diego | W99-93 | 14-1 | .933 | #7 | ESPN+ | Jenny Craig Pavilion · San Diego, CA |
| 16 | Fri Jan 2 | vs Seattle U | W80-72 (OT) | 15-1 | .938 | #7 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 17 | Sun Jan 4 | vs LMU | W82-47 | 16-1 | .941 | #7 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 18 | Thu Jan 8 | vs Santa Clara | W89-77 | 17-1 | .944 | #8 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 19 | Thu Jan 15 | at Washington St | W86-65 | 18-1 | .947 | #9 | CBSSN | Friel Court at Beasley Coliseum · Pullman, WA |
| 20 | Sat Jan 17 | atSeattle U | W71-50 | 19-1 | .950 | #9 | ESPN+ | Redhawk Center · Seattle, WA |
| 21 | Wed Jan 21 | vsPepperdine | W84-60 | 20-1 | .952 | #8 | ESPN+ | McCarthey Athletic Center · Spokane, WA |
| 22 | Sat Jan 24 | vs San Francisco | W68-66 | 21-1 | .955 | #8 | CBSSN | McCarthey Athletic Center · Spokane, WA |
| 23 | Sat Jan 31 | vs Saint Mary's | W73-65 | 22-1 | .957 | #6 | ESPN | McCarthey Athletic Center · Spokane, WA |
| 24 | Wed Feb 4 | at Portland | L80-87 | 22-2 | .917 | #6 | ESPN+ | Chiles Center · Portland, OR |
| 25 | Sat Feb 7 | at Oregon St | W81-61 | 23-2 | .920 | #6 | ESPN+ | Gill Coliseum · Corvallis, OR |
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