| 1 | Tue Nov 4 | at South Carolina | L72-91 | 0-1 | .000 | - | SECN+ | Colonial Life Arena · Columbia, SC |
| 2 | Mon Nov 10 | vs SC State | W85-62 | 1-1 | .500 | - | | Corbett Sports Center · Greensboro, NC |
| 3 | Thu Nov 13 | vs TBD | W89-83 | 2-1 | .667 | - | | Corbett Sports Center · Greensboro, NC |
| 4 | Tue Nov 18 | at Morgan St | W79-73 | 3-1 | .750 | - | ESPN+ | Hill Field House · Baltimore, MD |
| 5 | Fri Nov 28 | at Davidson | L74-90 | 3-2 | .600 | - | ESPN+ | John M. Belk Arena · Davidson, NC |
| 6 | Tue Dec 2 | at Charlotte | L57-74 | 3-3 | .500 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 7 | Sat Dec 6 | at NC Central | W69-54 | 4-3 | .571 | - | ESPN+ | McDougald-McLendon Arena · Durham, NC |
| 8 | Tue Dec 9 | at Howard | L69-73 | 4-4 | .500 | - | | Cameron Indoor Stadium · Durham, NC |
| 9 | Fri Dec 12 | vs MD-Eastern | W82-79 | 5-4 | .556 | - | | Corbett Sports Center · Greensboro, NC |
| 10 | Tue Dec 16 | at UNC Greensboro | W71-65 | 6-4 | .600 | - | ESPN+ | Greensboro Coliseum · Greensboro, NC |
| 11 | Sat Dec 20 | vsTBD | W95-55 | 7-4 | .636 | - | | Corbett Sports Center · Greensboro, NC |
| 12 | Mon Dec 29 | vs UNC Wilmington | L78-87 | 7-5 | .583 | - | CBSSN | Corbett Sports Center · Greensboro, NC |
| 13 | Wed Dec 31 | vs Northeastern | L74-85 | 7-6 | .538 | - | | Corbett Sports Center · Greensboro, NC |
| 14 | Sat Jan 3 | at Stony Brook | L80-81 | 7-7 | .500 | - | | Island FCU Arena · Stony Brook, NY |
| 15 | Thu Jan 8 | vs Elon | L64-69 | 7-8 | .467 | - | | Corbett Sports Center · Greensboro, NC |
| 16 | Thu Jan 15 | at William & Mary | L89-97 | 7-9 | .438 | - | | Kaplan Arena · Williamsburg, VA |
| 17 | Mon Jan 19 | at Hampton | L61-82 | 7-10 | .412 | - | CBSSN | Convocation Center (VA) · Hampton, VA |
| 18 | Thu Jan 22 | vs Hofstra | W79-78 | 8-10 | .444 | - | | Corbett Sports Center · Greensboro, NC |
| 19 | Sat Jan 24 | vs Towson | W80-73 | 9-10 | .474 | - | | Corbett Sports Center · Greensboro, NC |
| 20 | Thu Jan 29 | at Monmouth | L81-83 (OT) | 9-11 | .450 | - | | OceanFirst Bank Center · West Long Branch, NJ |
| 21 | Sat Jan 31 | at Drexel | L60-61 | 9-12 | .429 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 22 | Thu Feb 5 | at Charleston | L62-78 | 9-13 | .409 | - | | TD Arena · Charleston, SC |
| 23 | Sat Feb 7 | vs Campbell | L71-79 | 9-14 | .391 | - | | Corbett Sports Center · Greensboro, NC |
