| 1 | Mon Nov 3 | at #13Arizona | L87-93 | 0-1 | .000 | #3 | TNT | T-Mobile Arena · Las Vegas, NV |
| 2 | Thu Nov 6 | vs North Florida | W104-64 | 1-1 | .500 | #3 | SECN+ | O'Connell Center · Gainesville, FL |
| 3 | Tue Nov 11 | vs Florida St | W78-76 | 2-1 | .667 | #10 | SEC Network | O'Connell Center · Gainesville, FL |
| 4 | Sun Nov 16 | vs Miami | W82-68 | 3-1 | .750 | #10 | ESPN | O'Connell Center · Gainesville, FL |
| 5 | Fri Nov 21 | vs Merrimack | W80-45 | 4-1 | .800 | #10 | SECN+ | O'Connell Center · Gainesville, FL |
| 6 | Thu Nov 27 | vs TCU | L80-84 | 4-2 | .667 | #10 | FS1 | Jenny Craig Pavilion · San Diego, CA |
| 7 | Fri Nov 28 | vs Providence | W90-78 | 5-2 | .714 | #10 | FOX | Jenny Craig Pavilion · San Diego, CA |
| 8 | Tue Dec 2 | at #4Duke | L66-67 | 5-3 | .625 | #15 | ESPN | Cameron Indoor Stadium · Durham, NC |
| 9 | Tue Dec 9 | at #5UConn | L73-77 | 5-4 | .556 | #18 | ESPN | Gampel Pavilion · Storrs, CT |
| 10 | Sat Dec 13 | vs G Washington | W80-70 | 6-4 | .600 | #18 | ESPN2 | O'Connell Center · Gainesville, FL |
| 11 | Wed Dec 17 | vs St Francis PA | W102-61 | 7-4 | .636 | #23 | SEC Network | O'Connell Center · Gainesville, FL |
| 12 | Sun Dec 21 | vs Colgate | W90-60 | 8-4 | .667 | #23 | SECN+ | O'Connell Center · Gainesville, FL |
| 13 | Mon Dec 29 | vs Dartmouth | W94-72 | 9-4 | .692 | #22 | SEC Network | O'Connell Center · Gainesville, FL |
| 14 | Sat Jan 3 | at Missouri | L74-76 | 9-5 | .643 | #22 | SEC Network | Mizzou Arena · Columbia, MO |
| 15 | Tue Jan 6 | vs #18Georgia | W92-77 | 10-5 | .667 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 16 | Sat Jan 10 | vs #21Tennessee | W91-67 | 11-5 | .688 | - | ESPN | O'Connell Center · Gainesville, FL |
| 17 | Tue Jan 13 | at Oklahoma | W96-79 | 12-5 | .706 | #19 | ESPN2 | Lloyd Noble Center · Norman, OK |
| 18 | Sat Jan 17 | at #10Vanderbilt | W98-94 | 13-5 | .722 | #19 | ESPN | Memorial Gymnasium (TN) · Nashville, TN |
| 19 | Tue Jan 20 | vs LSU | W79-61 | 14-5 | .737 | #16 | ESPN2 | O'Connell Center · Gainesville, FL |
| 20 | Sat Jan 24 | vs Auburn | L67-76 | 14-6 | .700 | #16 | ESPN | O'Connell Center · Gainesville, FL |
| 21 | Wed Jan 28 | at South Carolina | W95-48 | 15-6 | .714 | #19 | SEC Network | Colonial Life Arena · Columbia, SC |
| 22 | Sun Feb 1 | vs #23Alabama | W100-77 | 16-6 | .727 | #19 | ABC | O'Connell Center · Gainesville, FL |
| 23 | Sat Feb 7 | at Texas A&M | W86-67 | 17-6 | .739 | #17 | SEC Network | Reed Arena · College Station, TX |
#25Kentucky
Ole Miss
Texas
#21Arkansas
Mississippi St