| 1 | Mon Nov 3 | at Cincinnati | L63-94 | 0-1 | .000 | - | ESPN+ | Fifth Third Arena · Cincinnati, OH |
| 2 | Sat Nov 8 | at #6Duke | L54-95 | 0-2 | .000 | - | The CW Network | Cameron Indoor Stadium · Durham, NC |
| 3 | Thu Nov 13 | vs TBD | W95-44 | 1-2 | .333 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 4 | Sun Nov 16 | vs Stetson | W76-65 | 2-2 | .500 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 5 | Wed Nov 19 | vs UNC Asheville | W80-73 | 3-2 | .600 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 6 | Sat Nov 22 | at Lipscomb | L62-83 | 3-3 | .500 | - | ESPN+ | Allen Arena · Nashville, TN |
| 7 | Sat Nov 29 | at High Point | L73-93 | 3-4 | .429 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 8 | Tue Dec 2 | vsTBD | W124-62 | 4-4 | .500 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 9 | Sat Dec 6 | at SC Upstate | L67-78 | 4-5 | .444 | - | ESPN+ | G.B. Hodge Center · Spartanburg, SC |
| 10 | Thu Dec 11 | at Virginia Tech | L74-96 | 4-6 | .400 | - | ACC Extra | Cassell Coliseum · Blacksburg, VA |
| 11 | Thu Dec 18 | at #25Georgia | L82-112 | 4-7 | .364 | - | SECN+ | Stegeman Coliseum · Athens, GA |
| 12 | Wed Dec 31 | vs Wofford | L74-79 | 4-8 | .333 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 13 | Sat Jan 3 | at Furman | W80-77 (OT) | 5-8 | .385 | - | ESPN+ | Timmons Arena · Greenville, SC |
| 14 | Wed Jan 7 | at Samford | L77-82 | 5-9 | .357 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 15 | Sat Jan 10 | at The Citadel | L77-79 (OT) | 5-10 | .333 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 16 | Wed Jan 14 | vs ETSU | W72-68 | 6-10 | .375 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 17 | Sat Jan 17 | vs Chattanooga | L82-90 | 6-11 | .353 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 18 | Wed Jan 21 | at Mercer | L76-88 | 6-12 | .333 | - | ESPN+ | Hawkins Arena · Macon, GA |
| 19 | Sat Jan 24 | vs VMI | W88-58 | 7-12 | .368 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 20 | Thu Jan 29 | atETSU | W90-88 | 8-12 | .400 | - | ESPN+ | Freedom Hall Civic Center · Johnson City, TN |
| 21 | Sun Feb 1 | vsSamford | L74-88 | 8-13 | .381 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 22 | Wed Feb 4 | at UNC Greensboro | L78-81 | 8-14 | .364 | - | ESPN+ | Greensboro Coliseum · Greensboro, NC |
| 23 | Sat Feb 7 | atWofford | L66-77 | 8-15 | .348 | - | ESPN+ | Jerry Richardson Indoor Stadium · Spartanburg, SC |
