| 1 | Mon Nov 3 | vs TBD | W119-60 | 1-0 | 1.000 | - | ESPN+ | The Field House · Commerce, TX |
| 2 | Wed Nov 5 | at New Mexico | L54-76 | 1-1 | .500 | - | | The Pit · Albuquerque, NM |
| 3 | Sun Nov 9 | at Hawai'i | L74-100 | 1-2 | .333 | - | ESPN+ | Stan Sheriff Center · Honolulu, HI |
| 4 | Fri Nov 14 | at Rice | L64-71 | 1-3 | .250 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 5 | Wed Nov 19 | vsTBD | W115-44 | 2-3 | .400 | - | ESPN+ | The Field House · Commerce, TX |
| 6 | Mon Nov 24 | at Fairleigh | W70-65 | 3-3 | .500 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 7 | Tue Nov 25 | at Army | W84-67 | 4-3 | .571 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 8 | Fri Dec 5 | at #5UConn | L59-83 | 4-4 | .500 | - | Peacock | Gampel Pavilion · Storrs, CT |
| 9 | Sun Dec 7 | vs C Arkansas | W75-68 | 5-4 | .556 | - | ESPN+ | The Field House · Commerce, TX |
| 10 | Fri Dec 12 | at McNeese | L66-102 | 5-5 | .500 | - | ESPN+ | Legacy Center · Lake Charles, LA |
| 11 | Mon Dec 15 | at SE Louisiana | W70-69 | 6-5 | .545 | - | ESPN+ | University Center (LA) · Hammond, LA |
| 12 | Sun Dec 21 | at Texas A&M | L77-118 | 6-6 | .500 | - | SECN+ | Reed Arena · College Station, TX |
| 13 | Mon Dec 29 | vs SF Austin | L48-75 | 6-7 | .462 | - | ESPN+ | The Field House · Commerce, TX |
| 14 | Wed Dec 31 | vs Lamar | L62-69 | 6-8 | .429 | - | ESPN+ | The Field House · Commerce, TX |
| 15 | Sat Jan 3 | at Nicholls | L58-80 | 6-9 | .400 | - | ESPN+ | David R. Stopher Gymnasium · Thibodaux, LA |
| 16 | Mon Jan 5 | at New Orleans | L73-83 | 6-10 | .375 | - | ESPN+ | Lakefront Arena · New Orleans, LA |
| 17 | Sat Jan 10 | vs UT Rio Grande | W77-69 | 7-10 | .412 | - | ESPN+ | The Field House · Commerce, TX |
| 18 | Mon Jan 12 | vs Texas A&M-CC | L50-61 | 7-11 | .389 | - | ESPN+ | The Field House · Commerce, TX |
| 19 | Sat Jan 17 | at Hou Christian | L70-81 | 7-12 | .368 | - | ESPN+ | Sharp Gymnasium · Houston, TX |
| 20 | Mon Jan 19 | at Incarnate Word | W80-58 | 8-12 | .400 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 21 | Sat Jan 24 | at N'Western St | PPD | 10-16 | .385 | - | | Prather Coliseum · Natchitoches, LA |
| 22 | Mon Jan 26 | atLamar | PPD | 10-16 | .385 | - | | Montagne Center · Beaumont, TX |
| 23 | Tue Jan 27 | atLamar | L61-82 | 8-13 | .381 | - | ESPN+ | Montagne Center · Beaumont, TX |
| 24 | Sat Jan 31 | vsNicholls | L68-72 | 8-14 | .364 | - | ESPN+ | The Field House · Commerce, TX |
| 25 | Mon Feb 2 | vsNew Orleans | L85-94 | 8-15 | .348 | - | ESPN+ | The Field House · Commerce, TX |
| 26 | Wed Feb 4 | atN'Western St | W74-68 | 9-15 | .375 | - | ESPN+ | Prather Coliseum · Natchitoches, LA |
| 27 | Sat Feb 7 | vsN'Western St | W52-48 | 10-15 | .400 | - | ESPN+ | The Field House · Commerce, TX |
| 28 | Mon Feb 9 | atSF Austin | L70-74 | 10-16 | .385 | - | ESPN+ | William R. Johnson Coliseum · Nacogdoches, TX |
