| 1 | Mon Nov 3 | at Colorado St | L64-98 | 0-1 | .000 | - | | Moby Arena · Fort Collins, CO |
| 2 | Fri Nov 7 | vs TBD | W104-60 | 1-1 | .500 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 3 | Tue Nov 11 | vsTBD | W109-70 | 2-1 | .667 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 4 | Sun Nov 16 | at Indiana | L61-69 | 2-2 | .500 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 5 | Thu Nov 20 | vs So Indiana | W87-81 | 3-2 | .600 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 6 | Sat Nov 22 | at High Point | L80-91 | 3-3 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 7 | Wed Nov 26 | vsTBD | W117-55 | 4-3 | .571 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 8 | Mon Dec 1 | vs McNeese | W71-67 | 5-3 | .625 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 9 | Sat Dec 6 | at Nicholls | L67-74 | 5-4 | .556 | - | ESPN+ | David R. Stopher Gymnasium · Thibodaux, LA |
| 10 | Mon Dec 8 | at New Orleans | L83-84 | 5-5 | .500 | - | ESPN+ | Lakefront Arena · New Orleans, LA |
| 11 | Mon Dec 15 | at TCU | L65-69 | 5-6 | .455 | - | ESPN+ | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 12 | Sun Dec 21 | vs N Arizona | W90-66 | 6-6 | .500 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 13 | Tue Dec 30 | vs SE Louisiana | W79-70 | 7-6 | .538 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 14 | Sat Jan 3 | vs Hou Christian | W73-56 | 8-6 | .571 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 15 | Mon Jan 5 | at UT Rio Grande | L67-80 | 8-7 | .533 | - | ESPN+ | UTRGV Fieldhouse · Edinburg, TX |
| 16 | Sat Jan 10 | at Lamar | L51-63 | 8-8 | .500 | - | ESPN+ | Montagne Center · Beaumont, TX |
| 17 | Mon Jan 12 | at SF Austin | L46-56 | 8-9 | .471 | - | ESPN+ | William R. Johnson Coliseum · Nacogdoches, TX |
| 18 | Sat Jan 17 | vs N'Western St | W76-74 | 9-9 | .500 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 19 | Mon Jan 19 | vs E Texas A&M | L58-80 | 9-10 | .474 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 20 | Sat Jan 24 | vs Texas A&M-CC | L71-79 | 9-11 | .450 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 21 | Tue Jan 27 | atHou Christian | L75-81 | 9-12 | .429 | - | ESPN+ | Sharp Gymnasium · Houston, TX |
| 22 | Sat Jan 31 | vsUT Rio Grande | L93-106 | 9-13 | .409 | - | ESPN+ | Alice P. McDermott Convocation Center · San Antonio, TX |
| 23 | Mon Feb 2 | atTexas A&M-CC | W71-69 | 10-13 | .435 | - | CBSSN | American Bank Center · Corpus Christi, TX |
| 24 | Sat Feb 7 | atMcNeese | L64-81 | 10-14 | .417 | - | ESPN+ | Legacy Center · Lake Charles, LA |
| 25 | Mon Feb 9 | atSE Louisiana | L62-74 | 10-15 | .400 | - | ESPN+ | University Center (LA) · Hammond, LA |
