| 1 | Mon Nov 3 | at Western KY | L70-82 | 0-1 | .000 | - | ESPN+ | E. A. Diddle Arena · Bowling Green, KY |
| 2 | Fri Nov 7 | at Charlotte | L65-70 | 0-2 | .000 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 3 | Mon Nov 10 | vs TBD | W118-58 | 1-2 | .333 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 4 | Thu Nov 13 | vsTBD | W86-64 | 2-2 | .500 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 5 | Mon Nov 17 | vs W Georgia | L59-61 | 2-3 | .400 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 6 | Wed Nov 19 | at SC Upstate | W88-84 | 3-3 | .500 | - | ESPN+ | G.B. Hodge Center · Spartanburg, SC |
| 7 | Wed Nov 26 | at #19Kentucky | L54-104 | 3-4 | .429 | - | SEC Network | Rupp Arena · Lexington, KY |
| 8 | Sat Nov 29 | at Georgia | L81-123 | 3-5 | .375 | - | SECN+ | Stegeman Coliseum · Athens, GA |
| 9 | Wed Dec 3 | at Lipscomb | L80-83 | 3-6 | .333 | - | ESPN+ | Allen Arena · Nashville, TN |
| 10 | Sat Dec 6 | atW Georgia | W87-59 | 4-6 | .400 | - | ESPN+ | The Coliseum · Carrollton, GA |
| 11 | Sat Dec 13 | vsTBD | W101-69 | 5-6 | .455 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 12 | Thu Dec 18 | vs SE Missouri St | W85-74 | 6-6 | .500 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 13 | Sat Dec 20 | vs UT Martin | L62-86 | 6-7 | .462 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 14 | Tue Dec 30 | vs Tennessee St | L76-88 | 6-8 | .429 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 15 | Thu Jan 1 | at Little Rock | L58-77 | 6-9 | .400 | - | ESPN+ | Jack Stephens Center · Little Rock, AR |
| 16 | Thu Jan 8 | at E Illinois | L61-71 | 6-10 | .375 | - | ESPN+ | Lantz Arena · Charleston, IL |
| 17 | Sat Jan 10 | at W Illinois | W59-54 | 7-10 | .412 | - | ESPN+ | LeRoy A. Ufkes Court at Western Hall · Macomb, IL |
| 18 | Thu Jan 15 | vs So Indiana | L54-71 | 7-11 | .389 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 19 | Sat Jan 17 | vs Morehead St | L70-76 | 7-12 | .368 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 20 | Thu Jan 22 | at Lindenwood | L68-89 | 7-13 | .350 | - | ESPN+ | placeholder · sf, ca |
| 21 | Sat Jan 24 | at SIUE | L58-62 | 7-14 | .333 | - | ESPN+ | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 22 | Sat Jan 31 | vsLittle Rock | W87-77 | 8-14 | .364 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 23 | Mon Feb 2 | atTennessee St | W90-85 | 9-14 | .391 | - | ESPN+ | Gentry Center · Nashville, TN |
| 24 | Thu Feb 5 | vsW Illinois | W97-72 | 10-14 | .417 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 25 | Sat Feb 7 | vsE Illinois | L54-60 | 10-15 | .400 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
