| 1 | Mon Nov 3 | at UAB | L55-106 | 0-1 | .000 | - | ESPN+ | Bartow Arena · Birmingham, AL |
| 2 | Wed Nov 5 | vs TBD | W97-61 | 1-1 | .500 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 3 | Fri Nov 7 | at Murray St | L60-108 | 1-2 | .333 | - | ESPN+ | CFSB Center · Murray, KY |
| 4 | Wed Nov 12 | at Hawai'i | L56-88 | 1-3 | .250 | - | ESPN+ | Stan Sheriff Center · Honolulu, HI |
| 5 | Fri Nov 14 | vs Utah Tech | L75-81 (2OT) | 1-4 | .200 | - | | Stan Sheriff Center · Honolulu, HI |
| 6 | Sat Nov 15 | at Manhattan | L73-80 | 1-5 | .167 | - | | Stan Sheriff Center · Honolulu, HI |
| 7 | Sat Nov 22 | at Bakersfield | L70-86 | 1-6 | .143 | - | ESPN+ | Icardo Center · Bakersfield, CA |
| 8 | Tue Nov 25 | at Texas A&M | L84-120 | 1-7 | .125 | - | SECN+ | Reed Arena · College Station, TX |
| 9 | Wed Dec 3 | at UL Monroe | L52-66 | 1-8 | .111 | - | ESPN+ | Fant-Ewing Coliseum · Monroe, LA |
| 10 | Mon Dec 8 | at Kansas St | L49-108 | 1-9 | .100 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 11 | Tue Dec 16 | vs Tarleton | L64-88 | 1-10 | .091 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 12 | Fri Dec 19 | at Florida St | L49-96 | 1-11 | .083 | - | ACC Extra | Donald L. Tucker Center · Tallahassee, FL |
| 13 | Mon Dec 22 | at West Virginia | L51-86 | 1-12 | .077 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 14 | Mon Dec 29 | at Oklahoma | L69-93 | 1-13 | .071 | - | SECN+ | Lloyd Noble Center · Norman, OK |
| 15 | Sat Jan 3 | vs Alabama St | L69-89 | 1-14 | .067 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 16 | Mon Jan 5 | vs Alabama A&M | L51-71 | 1-15 | .063 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 17 | Sat Jan 10 | at Prairie View | L69-70 | 1-16 | .059 | - | | William Nicks Building · Prairie View, TX |
| 18 | Mon Jan 12 | at Texas So | L51-84 | 1-17 | .056 | - | | H&PE Arena · Houston, TX |
| 19 | Sat Jan 17 | vs Bethune | L63-79 | 1-18 | .053 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 20 | Mon Jan 19 | vs FAMU | L48-62 | 1-19 | .050 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 21 | Wed Jan 28 | at Southern | L69-80 | 1-20 | .048 | - | | F. G. Clark Activity Center · Baton Rouge, LA |
| 22 | Sat Jan 31 | vs AR-Pine Bluff | L70-78 | 1-21 | .045 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 23 | Sat Feb 7 | vs Jackson St | L81-97 | 1-22 | .043 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 24 | Mon Feb 9 | vs Alcorn St | L66-74 | 1-23 | .042 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
Grambling