| 1 | Mon Sep 8 | at Bears | W27-24 | 1-0 | 1.000 | Soldier Field · Chicago, IL |
| 2 | Sun Sep 14 | vs Falcons | L6-22 | 1-1 | .500 | U.S. Bank Stadium · Minneapolis, MN |
| 3 | Sun Sep 21 | vs Bengals | W48-10 | 2-1 | .667 | U.S. Bank Stadium · Minneapolis, MN |
| 4 | Sun Sep 28 | at Steelers | L21-24 | 2-2 | .500 | Croke Park · Dublin, Ireland |
| 5 | Sun Oct 5 | at Browns | W21-17 | 3-2 | .600 | Tottenham Hotspur Stadium · London, England |
| --bye week-- |
| 7 | Sun Oct 19 | vs Eagles | L22-28 | 3-3 | .500 | U.S. Bank Stadium · Minneapolis, MN |
| 8 | Thu Oct 23 | at Chargers | L10-37 | 3-4 | .429 | SoFi Stadium · Inglewood, CA |
| 9 | Sun Nov 2 | at Lions | W27-24 | 4-4 | .500 | Ford Field · Detroit, MI |
| 10 | Sun Nov 9 | vs Ravens | L19-27 | 4-5 | .444 | U.S. Bank Stadium · Minneapolis, MN |
| 11 | Sun Nov 16 | vsBears | L17-19 | 4-6 | .400 | U.S. Bank Stadium · Minneapolis, MN |
| 12 | Sun Nov 23 | at Packers | L6-23 | 4-7 | .364 | Lambeau Field · Green Bay, WI |
| 13 | Sun Nov 30 | at Seahawks | L0-26 | 4-8 | .333 | Lumen Field · Seattle, WA |
| 14 | Sun Dec 7 | vs Commanders | W31-0 | 5-8 | .385 | U.S. Bank Stadium · Minneapolis, MN |
| 15 | Sun Dec 14 | at Cowboys | W34-26 | 6-8 | .429 | AT&T Stadium · Arlington, TX |
| 16 | Sun Dec 21 | at Giants | W16-13 | 7-8 | .467 | MetLife Stadium · East Rutherford, NJ |
| 17 | Thu Dec 25 | vsLions | W23-10 | 8-8 | .500 | U.S. Bank Stadium · Minneapolis, MN |
| 18 | Sun Jan 4 | vsPackers | W16-3 | 9-8 | .529 | U.S. Bank Stadium · Minneapolis, MN |
