| Sat Feb 21 | at Austin | 5:30 PM | 13-8-13 | 47 PTS | Q2 Stadium · Austin, TX |
| Sat Feb 28 | vs Cincinnati | 1:30 PM | 20-5-9 | 65 PTS | Allianz Field · Saint Paul, MN |
| Sat Mar 7 | at Nashville | 5:30 PM | 16-6-12 | 54 PTS | GEODIS Park · Nashville, TN |
| Sat Mar 14 | at Vancouver | 7:30 PM | 18-9-7 | 63 PTS | BC Place · Vancouver, BC |
| Sun Mar 22 | vs Seattle | 11:30 AM | 15-10-9 | 55 PTS | Allianz Field · Saint Paul, MN |
| Sat Apr 4 | at LA Galaxy | 7:30 PM | 7-9-18 | 30 PTS | Dignity Health Sports Park · Carson, CA |
| Sat Apr 11 | at San Diego | 7:30 PM | 19-6-9 | 63 PTS | Snapdragon Stadium · San Diego, CA |
| Sat Apr 18 | vs Portland | 5:30 PM | 11-11-12 | 44 PTS | Allianz Field · Saint Paul, MN |
| Wed Apr 22 | at Dallas | 5:30 PM | 11-11-12 | 44 PTS | Toyota Stadium · Frisco, TX |
| Sat Apr 25 | vs LAFC | 10:45 AM | 17-9-8 | 60 PTS | Allianz Field · Saint Paul, MN |
| Sat May 2 | at Columbus | 4:30 PM | 14-12-8 | 54 PTS | Lower.com Field · Columbus, OH |
| Sun May 10 | vsAustin | 4:00 PM | 13-8-13 | 47 PTS | Allianz Field · Saint Paul, MN |
| Wed May 13 | vs Colorado | 5:30 PM | 11-8-15 | 41 PTS | Allianz Field · Saint Paul, MN |
| Sat May 16 | at New England | 4:30 PM | 9-9-16 | 36 PTS | Gillette Stadium · Foxborough, MA |
| Sat May 23 | vs Salt Lake | 5:30 PM | 12-5-17 | 41 PTS | Allianz Field · Saint Paul, MN |
| Wed Jul 22 | at Kansas City | 5:30 PM | 7-7-20 | 28 PTS | Children's Mercy Park · Kansas City, KS |
| Sat Jul 25 | vsVancouver | 5:30 PM | 18-9-7 | 63 PTS | Allianz Field · Saint Paul, MN |
| Sat Aug 1 | vsSan Diego | 5:30 PM | 19-6-9 | 63 PTS | Allianz Field · Saint Paul, MN |
| Sat Aug 15 | atSalt Lake | 6:30 PM | 12-5-17 | 41 PTS | America First Field · Sandy, UT |
| Wed Aug 19 | vs Atlanta | 5:30 PM | 5-13-16 | 28 PTS | Allianz Field · Saint Paul, MN |
| Sat Aug 22 | at San Jose | 7:30 PM | 11-8-15 | 41 PTS | PayPal Park · San Jose, CA |
| Sat Aug 29 | vs Orlando | 5:30 PM | 14-11-9 | 53 PTS | Allianz Field · Saint Paul, MN |
| Sat Sep 5 | atPortland | 7:30 PM | 11-11-12 | 44 PTS | Providence Park · Portland, OR |
| Wed Sep 9 | vsDallas | 5:30 PM | 11-11-12 | 44 PTS | Allianz Field · Saint Paul, MN |
| Sat Sep 12 | at St. Louis | 5:30 PM | 8-8-18 | 32 PTS | Energizer Park · St. Louis, MO |
| Sat Sep 19 | vsLA Galaxy | 5:30 PM | 7-9-18 | 30 PTS | Allianz Field · Saint Paul, MN |
| Sat Sep 26 | atSeattle | 5:30 PM | 15-10-9 | 55 PTS | Lumen Field · Seattle, WA |
| Sat Oct 10 | vs Houston | 5:30 PM | 9-10-15 | 37 PTS | Allianz Field · Saint Paul, MN |
| Wed Oct 14 | atColorado | 6:30 PM | 11-8-15 | 41 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| Sat Oct 17 | vsSt. Louis | 1:30 PM | 8-8-18 | 32 PTS | Allianz Field · Saint Paul, MN |
| Sat Oct 24 | atHouston | 5:30 PM | 9-10-15 | 37 PTS | Shell Energy Stadium · Houston, TX |
| Wed Oct 28 | vsKansas City | 5:30 PM | 7-7-20 | 28 PTS | Allianz Field · Saint Paul, MN |
| Sun Nov 1 | atLAFC | 12:00 PM | 17-9-8 | 60 PTS | BMO Stadium · Los Angeles, CA |
| Sat Nov 7 | vsSan Jose | 4:00 PM | 11-8-15 | 41 PTS | Allianz Field · Saint Paul, MN |
