| 1 | Sat Aug 30 | at Kentucky | L16-24 | 0-1 | .000 | Kroger Field · Lexington, KY |
| 2 | Sat Sep 6 | vs Western KY | W45-21 | 1-1 | .500 | Glass Bowl · Toledo, OH |
| 3 | Sat Sep 13 | vs Morgan St | W60-0 | 2-1 | .667 | Glass Bowl · Toledo, OH |
| 4 | Sat Sep 20 | at W Michigan | L13-14 | 2-2 | .500 | Waldo Stadium · Kalamazoo, MI |
| 5 | Sat Sep 27 | vs Akron | W45-3 | 3-2 | .600 | Glass Bowl · Toledo, OH |
| 6 | Sat Oct 11 | at Bowling Green | L23-28 | 3-3 | .500 | Doyt L. Perry Stadium · Bowling Green, OH |
| 7 | Sat Oct 18 | vs Kent State | W45-10 | 4-3 | .571 | Glass Bowl · Toledo, OH |
| 8 | Sat Oct 25 | at Washington St | L7-28 | 4-4 | .500 | Gesa Field · Pullman, WA |
| 9 | Wed Nov 5 | vs N Illinois | W42-3 | 5-4 | .556 | Glass Bowl · Toledo, OH |
| 10 | Wed Nov 12 | at Miami OH | W24-3 | 6-4 | .600 | Yager Stadium · Oxford, OH |
| 11 | Sat Nov 22 | vs Ball State | W38-9 | 7-4 | .636 | Glass Bowl · Toledo, OH |
| 12 | Sat Nov 29 | at C Michigan | W21-3 | 8-4 | .667 | Kelly/Shorts Stadium · Mount Pleasant, MI |
Louisville