| Fri Aug 15 | vs B'mouth | W4-2 | 1-0-0 | 3 PTS | Anfield · Liverpool, England |
| Mon Aug 25 | at Newcastle | W3-2 | 2-0-0 | 6 PTS | St. James' Park · Newcastle, England |
| Sun Aug 31 | vs Arsenal | W1-0 | 3-0-0 | 9 PTS | Anfield · Liverpool, England |
| Sun Sep 14 | at Burnley | W1-0 | 4-0-0 | 12 PTS | Turf Moor · Burnley, England |
| Sat Sep 20 | vs Everton | W2-1 | 5-0-0 | 15 PTS | Anfield · Liverpool, England |
| Sat Sep 27 | at C Palace | L1-2 | 5-0-1 | 15 PTS | Selhurst Park · London, England |
| Sat Oct 4 | at Chelsea | L1-2 | 5-0-2 | 15 PTS | Stamford Bridge · London, England |
| Sun Oct 19 | vs Man Utd | L1-2 | 5-0-3 | 15 PTS | Anfield · Liverpool, England |
| Sat Oct 25 | at Brentford | L2-3 | 5-0-4 | 15 PTS | Gtech Community Stadium · Brentford, England |
| Sat Nov 1 | vs A Villa | W2-0 | 6-0-4 | 18 PTS | Anfield · Liverpool, England |
| Sun Nov 9 | at Man City | L0-3 | 6-0-5 | 18 PTS | Etihad Stadium · Manchester, England |
| Sat Nov 22 | vs Nott'm Forest | L0-3 | 6-0-6 | 18 PTS | Anfield · Liverpool, England |
| Sun Nov 30 | at West Ham | W2-0 | 7-0-6 | 21 PTS | London Stadium · London, England |
| Wed Dec 3 | vs Sunderland | D1-1 | 7-1-6 | 22 PTS | Anfield · Liverpool, England |
| Sat Dec 6 | at Leeds | D3-3 | 7-2-6 | 23 PTS | Elland Road · Leeds, England |
| Sat Dec 13 | vs Brighton | W2-0 | 8-2-6 | 26 PTS | Anfield · Liverpool, England |
| Sat Dec 20 | at Spurs | W2-1 | 9-2-6 | 29 PTS | Tottenham Hotspur Stadium · London, England |
| Sat Dec 27 | vs Wolves | W2-1 | 10-2-6 | 32 PTS | Anfield · Liverpool, England |
| Thu Jan 1 | vsLeeds | D0-0 | 10-3-6 | 33 PTS | Anfield · Liverpool, England |
| Sun Jan 4 | at Fulham | D2-2 | 10-4-6 | 34 PTS | Craven Cottage · London, England |
| Thu Jan 8 | atArsenal | D0-0 | 10-5-6 | 35 PTS | Emirates Stadium · London, England |
| Sat Jan 17 | vsBurnley | D1-1 | 10-6-6 | 36 PTS | Anfield · Liverpool, England |
| Sat Jan 24 | atB'mouth | L2-3 | 10-6-7 | 36 PTS | Vitality Stadium · Bournemouth, England |
| Sat Jan 31 | vsNewcastle | W4-1 | 11-6-7 | 39 PTS | Anfield · Liverpool, England |
| Sun Feb 8 | vsMan City | L1-2 | 11-6-8 | 39 PTS | Anfield · Liverpool, England |
